Cardiovascular Disease is a condition of the heart that includes diseased vessels, blood clots and coronary structural problems. 

High cholesterol, also known as hypercholesterolemia, is a major risk factor for heart disease and stroke. Abnormal levels of LDL cholesterol or HDL cholesterol are treated with a low-fat diet, exercise, and medications such as statins.


When you have high cholesterol, the first thing to do is to change your diet and fitness: less saturated fat, no trans-fat, and more activity.

If that doesn’t bring down your “bad” (LDL) cholesterol enough, your doctor may suggest that you also take medicine to help out, while keeping a healthy diet and exercise regime. 

There are several different types of prescription drugs that lower LDL.  The Most Common Cholesterol Meds: Statins

These are usually the first type of drug that doctors prescribe to lower LDL. They also lower triglycerides, which are another type of blood fat, and mildly raise your "good" (HDL) cholesterol.

The Newest Type of Drug: PCSK9 Inhibitors.  These drugs are used in people who can’t manage their cholesterol through lifestyle and statin treatments. They block a protein called PCSK9 to make it easier for the body to remove LDL from your blood.

They are mainly used in adults who inherit a genetic condition called “heterozygous familial hypercholesterolemia” that makes it hard to bring down their cholesterol level, or for people who had heart disease and need more than a statin. You get them as a shot every 2 weeks.



ENTRESTO is a prescription medicine used to reduce the risk of death and hospitalization in people with certain types of long-lasting (chronic) heart failure. It may help you live longer and lower your chance of having to go to the hospital for heart failure. This product contains 2 medications that work by relaxing blood vessels so that blood can flow more easily, which makes it easier for your heart to pump blood to your body.


PRALUENT (alirocumab) is an injectable prescription medicine used along with diet and statin therapy in adults to lower high levels of LDL (bad cholesterol) in the blood. Praluent works in the liver to increase clearing of the LDL.


Repatha (evolocumab) is a prescription medication indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of adults with familial high cholesterol or clinical atherosclerotic cardiovascular disease, who require additional lowering of LDL cholesterol. It works by inhibiting a certain antibody thereby reducing your cholesterol levels.

More Information

Adherence to therapy is critical to avoid the long term effects of high cholesterol, which could be a cardiovascular event or stroke.